KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2C
All Species:
27.27
Human Site:
S222
Identified Species:
50
UniProt:
Q06413
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06413
NP_002388.2
473
51221
S222
G
Y
G
N
P
R
N
S
P
G
L
L
V
S
P
Chimpanzee
Pan troglodytes
XP_001139828
503
54271
G220
L
T
V
P
N
G
A
G
S
S
P
V
G
N
G
Rhesus Macaque
Macaca mulatta
XP_001086412
483
52310
S240
G
Y
G
N
P
R
N
S
P
G
L
L
V
S
P
Dog
Lupus familis
XP_858441
472
51065
S221
G
Y
G
N
P
R
N
S
P
G
L
L
V
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFN5
474
51260
S222
G
Y
G
N
P
R
N
S
P
G
L
L
V
S
P
Rat
Rattus norvegicus
Q2MJT0
495
53235
G221
L
T
V
P
N
G
A
G
N
G
P
V
G
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510456
503
54885
S252
G
Y
G
N
P
R
N
S
P
G
L
L
V
S
P
Chicken
Gallus gallus
Q9W6U8
499
53650
N229
P
V
G
N
G
V
W
N
S
R
A
S
P
S
L
Frog
Xenopus laevis
Q03413
498
54053
S231
G
Y
I
S
A
R
A
S
P
G
L
L
P
V
S
Zebra Danio
Brachydanio rerio
NP_571387
465
49956
S221
G
Y
G
N
H
R
N
S
P
G
L
L
V
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
S222
G
S
P
S
P
G
P
S
P
G
I
A
H
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
R24
R
Q
V
T
F
S
K
R
R
S
G
L
L
K
K
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
H209
H
V
A
N
E
A
I
H
R
N
F
M
N
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.4
93.3
99.1
N.A.
98.7
56.5
N.A.
93
63.1
56.6
79.4
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
74.3
94.8
99.3
N.A.
99.7
69.2
N.A.
94
74.1
70.4
88.5
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
6.6
N.A.
100
20
53.3
93.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
100
26.6
60
93.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.7
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
24
0
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
62
0
54
0
8
24
0
16
0
70
8
0
16
0
16
% G
% His:
8
0
0
0
8
0
0
8
0
0
0
0
8
8
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
16
8
% K
% Leu:
16
0
0
0
0
0
0
0
0
0
54
62
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
62
16
0
47
8
8
8
0
0
8
16
0
% N
% Pro:
8
0
8
16
47
0
8
0
62
0
16
0
16
0
47
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
54
0
8
16
8
0
0
0
0
8
% R
% Ser:
0
8
0
16
0
8
0
62
16
16
0
8
0
54
8
% S
% Thr:
0
16
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
16
24
0
0
8
0
0
0
0
0
16
47
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _